Details of the Drug

General Information of Drug (ID: DML0GZ2)

Drug Name

Lead acetate

Synonyms

LEAD ACETATE; Lead diacetate; Lead(II) acetate; Lead(2+) acetate; 301-04-2; Acetic acid, lead salt; Unichem PBA; Lead di(acetate); Normal lead acetate; Dibasic lead acetate; Lead dibasic acetate; Bleiacetat [German]; lead(2+) diacetate; Plumbous acetate; Salt of saturn; Sugar of lead; Caswell No. 523A; Lead acetate (anhydrous); RCRA waste number U144; Acetate de plomb [French]; Lead acetate (Pb(Ac)2); Acetic acid lead(2+) salt; CCRIS 356; Acetic acid, lead(2+) salt; Acetic acid, lead(2 +) salt; UNII-KL498O6790; Acetate de plomb

Indication

Disease Entry	ICD 11	Status	REF
Discovery agent	N.A.	Investigative	[1]

Drug Type

Small molecular drug

Structure

3D MOL

2D MOL

#Ro5 Violations (Lipinski):
0

Molecular Weight

325

Topological Polar Surface Area

Not Available

Rotatable Bond Count

0

Hydrogen Bond Donor Count

0

Hydrogen Bond Acceptor Count

4

Chemical Identifiers

Formula: C4H6O4Pb
IUPAC Name: lead(2+);diacetate
Canonical SMILES: CC(=O)[O-].CC(=O)[O-].[Pb+2]
InChI: InChI=1S/2C2H4O2.Pb/c2*1-2(3)4;/h2*1H3,(H,3,4);/q;;+2/p-2
InChIKey: GUWSLQUAAYEZAF-UHFFFAOYSA-L

Cross-matching ID

PubChem CID: 9317
CAS Number: 301-04-2
TTD ID: D0S4VW

Molecular Interaction Atlas of This Drug

Drug Therapeutic Target (DTT)

DTT Name	DTT ID	UniProt ID	MOA	REF
Ferrochelatase (FECH)	TTQ6VF4	HEMH_HUMAN	Inhibitor	[1]

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Molecular Interaction Atlas (MIA)

MIA Detail

Jump to Detail Molecular Interaction Atlas of This Drug

References

1	Ferrochelatase, a novel target for photodynamic therapy of cancer. Oncol Rep. 1999 Nov-Dec;6(6):1439-42.
2	How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
3	Low-dose methotrexate enhances aminolevulinate-based photodynamic therapy in skin carcinoma cells in vitro and in vivo. Clin Cancer Res. 2009 May 15;15(10):3333-43.